CV

PhD

Sabanci University

Molecular Biology and Bioengineering

MSc

Albert Ludwigs University of Freiburg

Chemistry

BSc

Middle East Technical University

Chemistry

Doctoral Researcher

Sabanci University, Multiscale Interactions and Dynamical Systems (MIDST) lab

• Investigated the allosteric regulation of fluorescence in protein-based biosensors with classical and enhanced molecular dynamics simulations - supervised by Prof. Canan Atilgan
• Performed Perturbation Response Scanning (PRS) to identify allosteric sites most suitable for insertion of reporter domains.
• Employed Alphafold2 with a focus on obtaining alternative conformations.
• Designed and ranked binding site and allosteric mutants in terms of ligand affinity using steered-MD simulations. Results are complemented by wet-lab experiments.

Research Scientist

İlko Pharmaceuticals, Teknopark İstanbul

• Worked as an industrial PhD candidate in collaboration with Sabanci University on development of anti-cancer antibodies.
• Developed liquid chromatography-mass spectrometry methods for characterization of therapeutic antibodies from mammalian expression systems; identified post-translational modifications including glycans, charge variants, disulfide shuffling, aggregation, and stability.
• Involved in tech transfer from South Korean partner company Genexine.

Research Assistant

Albert Ludwigs University of Freiburg

• Worked as a Master's student in the group of Prof. Susana Andrade.
• Purified the ammonium transporter Amt1 and performed electrophysiology and Cryo-TEM to quantify the electrogenic ion current per monomer.